| Date:
2005-04-18
The
Japan Coleotherapy and Cancer
Nakatani
T. Konishi T. Miyahara K. Noda N. Three
novel cantharidin-related compounds from the Chinese blister
beetle, Mylabris phalerata Pall. Chemical & Pharmaceutical
Bulletin. 52(7):807-9, 2004 Jul.
Institution
Faculty of Pharmaceutical Sciences, Setsunan
University, Osaka, Japan.
Abstract
Three novel cantharidin analogues were isolated from the
Chinese blister beetle, Mylabris phalerata PALL. (Meloidae),
which has been used in traditional Chinese medicine for the
treatment of cancer. Their structures were determined on the
basis of heteronuclear multiple-bond connectivity and nuclear
Overhauser effect spectroscopy experiments, and chemical data
confirmed them to be so-called cantharimides, in which the
anhydride oxygen atoms are replaced by the basic amino acid L-lysine,
L-ornithine, and L-arginine moieties.
Special
Thanks José Conseco ( Lima Perú )
La
Coleoterapia y el Cáncer en Japón
Estamos traduciendo al Español.... ( Lunes 18 de Abril
del 2005)
utilizan
otro coleóptero el (
Mylabris phalerata
Pallas
)
ya lo tienen procesado en un medicamento, Publicitan su
investigación en el Boletín farmacéutico
|